As a natural barrier, they form the border between several nations. In the south, the mountains form the western border of Nirmathas and separate dark Nidal and Molthune. In the north, they form the border between Varisia and the Hold of Belkzen, Nirmathas and Nidal.
The northern section of the Mindspin Mountains, particularly between Varisia and the Hold of Belkzen, is considered a death-trap to all but the most experienced explorers. They are filled with giants (including fire giants), ogres, trolls, and all other manner of dangerous beasts. The abundance of such unpleasant life may be one of the reasons that the Mindspin Mountains form such an effective border between the two nations. The Broken Spine orc tribe occupy an abandoned keep in the eastern foothills of the Mindspin Mountains within the Hold of Belkzen.
The mountains are also populated by dwarves—mostly trappers and miners—who have settlements in the area. They explore the mountains, eager to uncover evidence of their old ancestral homes. Troops from nearby Janderhoff also patrol the region in an effort to ensure the security of locations that interest them, such as Crystalrock.
The central reaches of Mindspin Mountains near the Bloodsworn Vale are inhabited by the flame drakes who escaped the taming of the Vale in 4707 AR. These violent draconic creatures have begun conspiring with both giants and evil fey to wreak a terrible vengeance on the Bloodsworn Vale's civilised inhabitants.
The southern tip of the mountain range, between the nations of Nidal and Molthune, is home to Tintavex, a unique half-dragon griffon born from a magical accident. The range is also home to the Juggerloathe, the hellish spawn of a bulette and Lamashtu's divine herald Yethazmari that has menaced the regions for centuries, sometimes regurgitating its victims as terrifying undead bodaks.
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